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IRIC safety alert

MHRA Medical Device Safety Information – MDSI2405

Published on 23 April 2024

From: Health Facilities Scotland

MDSI2405 - Symbios ORIGIN® Posterior Stabilised Patient-Matched Total Knee Replacement Device: Risk of Early Revision



The MHRA was alerted by Beyond Compliance and the UK National Joint Registry (NJR) to a significantly higher revision rate observed with the ORIGIN PS patient-matched total knee replacement. Devices are being recalled as outlined in the FSN issued by the manufacturer.